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العنوان
GENE POLYMORPHISM IN NON-ALCOHOLIC FATTY LIVER DISEASE IN EGYPTIANS /
المؤلف
Mahmoud, Mervat Megahed El-Sayed.
هيئة الاعداد
باحث / مرفت مجاهد السيد محمود
مشرف / زكريا عبد الحليم محمد الخياط
مناقش / مجدى محمود محمد
مناقش / سها محمد حمدي
الموضوع
FATTY LIVER. GENE POLYMORPHISM.
تاريخ النشر
2023.
عدد الصفحات
289 p. ;
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الكيمياء الحيوية ، علم الوراثة والبيولوجيا الجزيئية
تاريخ الإجازة
1/1/2023
مكان الإجازة
جامعة الفيوم - كلية التربية - قسم الكيمياء
الفهرس
Only 14 pages are availabe for public view

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from 288

Abstract

The biochemical parameters in NAFLD group showed significantly elevated WBCs count; NFS; ALT; AST; TG; direct bilirubin; FBS; serum insulin and HOMA-IR when compared with control and showed significant decrease in both albumin level and PLT count. There were no significant differences regarding genotypic and allelic frequencies among NAFLD subjects and control individuals. Fibrosis progression estimated by NFS may be accompanied with higher age, PLTs, WBCs count, Hb and TG significantly decreased while INR, AST, total and direct bilirubin, FBS and HOMA-IR increased in correlation with level of fibrosis. Genotype frequencies differed significantly among the different fibrosis stages groups. CG+GG genotype carriers showed significantly higher age and ALT while lower WBCs count with fibrosis progression.