الفهرس 
Histological Study on the Effect of Erythropoietin in Isoproterenol Induced Myocardial Injury in Male Rats: Possible Role of Endogenous Stem Cells
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Abstract
The aim of the present work was to investigate the effect of erythropoietin (Epo) on isoproterenol (Iso) induced myocardial injury in male rats. The possible role of the endogenous stem cells related to the therapeutic effect of Epo was assessed. Thirty six adult male albino rats were divided into group I, six rats received 0.5ml saline/0.5ml distilled water/both by subcutaneous injection (SCI) under the skin of the back. group II (Epo Group), ten rats received Epo by SCI daily for 4 days at a dose of 5000 U/kg under the skin of the back. group III (Iso Group), ten rats given Iso (200 mg/kg) dissolved in saline by SCI under the skin of the back for two consecutive days. group IV (Combined Iso and Epo Group), ten rats received Iso and Epo in the same dose, by the same route and for the same duration as in Iso and Epo groups respectively. Each group was subdivided into subgroups a and b according to time of sacrifice, 2 and 4 weeks respectively. Creatine kinase-MB (CK-MB) cardiac enzyme was estimated 24 hours and 4 weeks following injections. Histological, morphometric and statistical studies were performed