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العنوان
Uses of nitriles and carbonyl compounds in the synthesis of biologically active heterocyclic compounds /
الناشر
Aya Elsayed Elsayed Khedr ,
المؤلف
Aya Elsayed Elsayed Khedr
هيئة الاعداد
باحث / Aya Elsayed Elsayed Khedr
مشرف / Raafat Milad Mohare
مشرف / Raafat Milad Mohareb
مشرف / Raafat Milad Mohareb
تاريخ النشر
2016
عدد الصفحات
139 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Organic Chemistry
تاريخ الإجازة
20/6/2017
مكان الإجازة
جامعة القاهرة - كلية العلوم - Organic Chemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

In this work the reaction of ethylacetoacetate (1) with Ü-naphthylamine (2) gave the N-(Naphthalen-1-yl)-3-oxobutanamid (3). The latter products underwent a series of heterocyclization reactions to yield pyridine, pyran, thiophene and pyrazole derivatives. The antitumor evaluations of the newly synthesized products against three cancer cell lines were measured