الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Idiopathic thrombocytopenic purpura (ITP) is an acquired autoimmune disease with many immune dysfunctions . Cytotoxic T lymphocyte antigen 4 (CTLA-4) is a T- lymphocyte surface molecule that can down modulate and terminate immune responses . Recently several studies have confirmed that some polymorphisms of this gene can influence its expression level therefore speculating that they might be associated with autoimmune diseases