الفهرس | Only 14 pages are availabe for public view |
Abstract Transurethral resection of the prostate (TURP) is the commonest operation performed on men over the age o£ 65 and has a low morbidi ty, and per i-opera ti ve mortality rate of less than tt:. However, preventable infectious complica tions in terms of urinary tract infections and septicaemia may jeopardize the post-operative period and cause dea th in a f’ew cases. The present study was aiming at the determination of’ the effecti vness of antibiotic prophylaxis used to prevent post TURP infective complica tions. The study was carried out on 103 patients who underwent TU RP at the department of urology, Alexandria University Hospi tal and the Medical Research Institute, over the period from March t990 to July 1991. Out of’ those 103 pa tien ts 23 with prooperative bacteruria were excluded and the remaining 80 pa tients were allocated to the following three short term antibiotic schedules: Group 1: (30 patients) Received 500 mg ampicilHn/ 6 hours and 80 mg gentamicin/8hours post-opera ti vely for 5 days. Group 11: (25 pateints) Received 500 mg amikacin LV 2hours pre-operatively and a second dose intraoperatively. Group 111: (25 pa tients) Received t mg cefoperazone 2 hours pr e - 0 per a ti vel y and a second dose intra-operatively. In addition to the preopera ti ve urine samples the following samples were taken -from each patient: If At opera tion: Prosta tic chips for culture. If Post-opera ti ye: follow. up urine samples on the 1st, 2nd. 3rd and 5th post-opera ti ve days, and catheter tip after its removal usually 40 hours postoperat1vely. Results: i Post-opera ti ve urinary tract infection developed in 26 (32.50) of pa tients, 25 (43.11) of these were in the Alexandria University Hospi tal, and only 1 (4.54) in the Medical Research Institute. |