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Abstract The aim of this study is to evaluate and compare the role of US, CT and MRI in characterization of the adrenal lesions .The present study was carried out on 45 patients; 24 males and 21 females. Their ages ranged from 1.5 to 70 years. They were referred from Oncology,Pediatric, General Surgery, Cardiology and Internal Medicine Departments, Zagazig University Hospitals in the period from January to June 2003, The histopathologic diagnosis was 16 cases of metastases, 6 cases of neuroblastoma, 6 cases of lymphoma,S cases of adenoma, 4 cases of carcinoma, 3 cases of pheochromocytoma, 2 cases of cavernous lymphangioma, 2 cases of cortical hyperplasia and I case of myelolipoma |