الفهرس 
Acknowledgement
Infection of NewbornOnly 14 pages are availabe for public view
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Abstract
The study included 120 infected newborns aged few hours to 17 days (77 males and 43 females), admitted to the special care baby unit (SCBU), Assiut University Hospital.
Full clinical evaluation including obstetric, natal and neonatal history were performed with special regards to some risk factors (low social class, maternal age parity, maternal disease or fever, premature rupture of membranes, prolonged rupture of membranes 18 hours, repeated unvlean vaginal examination, prolonged or complicated delivery, foul smelling liquor, birth trauma, prematurity and low birth weigh, umbilical catheterization). The predictive perinatal score for sepsis neonatorum was calculated for all the studied cases (Parmer, 1985), all cases were subjected to the following investigations hemoglobin estimation, total and differential leucocytic count with calculation of immature/total neutrophil ratio, detection of neutrophil vacuolization or toxic granulation, platelets count, urine culture, blood culture for both aerobic and anaerobic bacteria, chemical examination and culture of the C.S.F, liver function tests [Serum bilirubin level, serum alanine aminotransferase (A.L.T., S.G.P.T.), serum aspartate aminotrane (A.S.T, S.G.O.T) and alkaline phosphatase levels], and estimation of blood glucose level as well as serum levels of sodium and calcium.
among the studied cases 80.83% showed positive blood cultures. Significantly higher rates of maternal fever before or during labor, history suggestive of maternal urinary tract infection, repeated unclean vaginal examination, prolonged rupture of membranes for more than 18 hours and foul semelling liquor prematurity, low birth weight, male sex, umbilical catheterization and significant predictive perinatal score for sepsis neonatorum were found in septicemic neonates than in neonates with negative blood cultures.
Septicemic cases showed significantly higher frequencies of temperature instability, poor feeding, tachycardia, apnea, jaundice, omphalitis, vomiting and abdominal distension than cases with negative blood cultures.