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Abstract Tuberculosis is one of the diseases known ancient human civilizations and still participates human suffering as it affects 8-10 million and kills million persons per year. This study was performed with the following aims: 1. Determination’ prevalence of TB infection of the among first grade primary children school Alexa nd r ia and household contacts of the infected pupils. 2. Assessment of the efficacy of tuberculin test detection of TB in the community. 3. To study some factors related to for in 3 in the in the occurrence of the TB infection. Tuberculin test is the traditional method diagnosing infection with M. tuberculosis. currently available tuberculin tests are not sensitive or specific,but no better diagnostic for The 100method have yet been devised. It is the classical example of the delayed cellular hypersensitivity to some immuno reacti ve substances the These tubercle bacilli. of substaces present in their cultural extract ”tubercu lin”. There of the Old tuberculin, two types are Tuberculin and Protein Purified The Derivative. the latter was used in performing this study. The study sample amounted They to 1995 pupils. were chosen randomly from the six educational -regions of Alexandr ia by the proportional allocation method. pupils in Middle and Amrya regions into were divided two strata urban and rural where pupils of both strata were chosen proportional method. by allocation Tuberculin test was performed for these pupils. Houses of the tuberculin positive pupils were visited where tuberculin performed household their for test was contacts. A questionnaire was conducted through inter view with Tuberculin each member of family. the positi ve household submitted contacts to were radiological and bacteriological examination in the affiliated chest dispensary. The study revealed the following main results: 1. The prevalence of TB infection among first grade primary school pupils was 4.49. 2. Among household the prevalence contacts of the infected pupils of TB infection was fO,und to be 30.6. 3. positive tuberculin household contacts with radiological lesions compatible wi th TB constituted 3.6 of the whole household contacts. 4. The prevalence of positive tuberculin smear positive household contacts was 1.8of the whole household contacts. 5. Tuberculin test was proved as a tool for detection of TB in the community. 6. TB infection among- household contacts was found to be directly age related the and to crowding index, but had inverse relation with an educational level and income per capita. 7. percent of patients (as by proved Large TB radiological bacteriological examination) or reported symptoms suggestive of TB. The following are the main recommendations: 1. Annual tuberculin first primary test of grade school children should be performed as a tool for detection of TB among them and their household contacts. 2. With limited finding resources or manpower case can be accomplished investigation of by symptomatic persons especially prolonged cough. 3. Incorporation of tuberculin test in routine the pre-employment examinations. 4. Health education program must be initiated among slum inhabitants. 5. Improvement of the housing conditions areas in with high prevalence of TB infection. |