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Abstract creased damage to red blood solution (glucose effect on values reports incidence of neonatal infant, others deny it ex ri ci C c>nc7usion its have suggested an increased incidence of stated that shortening of oxytocin for induction of immaturity, anoxic liver transfusion, Several repo neonatal jaundice have suggest infants been a S rrwria r- in the 5%) serum ect subj of controversy, occurance of hyponatremia hyperbilirubinemia in the following the use of cells. alone bilirubin, serum sodium and hematocrite While some authors with increased corresponding red labour is usually damage, the duration of by the use of associated with liver enhanced placentofetal blood cell fragility and mechamical Also, the infused electrolyte free or as a vehicle for oxytocin and its oxytocin. pregnancy Some authors The present study is a prospective study including 100 full term pregnant mothers and their newborns divided into three administr groups to show the effect of oxytocin and intravenous fluid ation on serum bilirubin level in newborn infants. 98 Our findings imply that has infusion of oxytocin during labour a definite role in the pathogenesis of a and this neonatal The infusion hyperbilirubinemi occurs in a dose dependent manner. of large amount of electrolyte free fluid with ease oxytocin increases its effect in intravenous fluid only without ox to ytocin was not shown produce the same effect. The peak of hyperbilirubinemia was found to be in the 4th day post-natally. Some other factors in this study showed sign relationship with serum bilirubin levels in the newborns , maternal gravidity and rns as perinatal asphyxia. However regarding may have been re reas in gravidity s such as feedi maternal gravidity the effect lated to concomitant ox may administration which causes such increase factor i level of serum bilirubin rather than the matavidity itself. Other infant, contrace ng of the infant, maternal ptive pill usa to age, sex of the ge prior to Pregnancy and maternal infants. ma and fetal serum sodium did not affect serum bilirubin in newborn It is concluded that maternal infusion with oxytocin has a definite dose dependant role in the pathogenesis of neonatal hyperbilirubinemia. Oxytocin should therefore be administered 99 with great caution in small doses when indicated in small amounts of intravenous fluids and as they may also play a secondary role of lesser magnitude. |