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Abstract Assessment of phagocytic function of PMN leucocytes by Wilkinson Technique (1977) was performed on 15 asthmatic children (8 males & 7 females) aged 3 to 11 years and on 15 normal children (8 males & 7 females) of the same age group, in order to elucidate. The pathogenesis of their increased predisposition to upper respiratory tract infections. For all cases the following were done: - Full history taking - Clinical examination - X-ray film - Special tests a- complete blood picture b- Phagocytosis (Wilkinson, 1977). The patients were divided into two groups: Group (I) Consisted of 15 patients (8 males and 7 females), In whome asthmatic attacks are well established. group (II): ”Control group” consisted of 15 apparently healthy subjects (8 males and 7 females). -106- The elevated total leucocytic count and absolute P.M.N count in group I than those of group II denoting the role of infection as a precipitating factor. A high significant reduction percentage by uSIng either pooled or asthmatic patients than control group. In phagocytic patient serum In Also, a high significant reduction In phagocytic index by uSIng either pooled or patient serum In asthmatic patients than control group. In conclusion, our results denote that atopic asthmatic children have defect in phagocytic function of P.M.N such situation makes those patients more prone to respiratory infection. |