الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Pre-eclampsia remains to be one of the most commonly encountered pregnancy related disorder in the world. Pre-eclampsia is a multisystem disorder affecting virtually every organ and system in the body , the traditional diagnostic features , representing two facets of a complex pathophysiological process The common pathological feature of the disease , whether in the decidual vessels of the placental bed, renal microvasculature , liver, heart or cerebral circulation , is vascular endothelial damage and dysfunction Current hypothesis propose that pre-eclampsia is due to widespread maternal endothelial cell damage , perhaps secondry to a cytotoxic factor released by the trophoblast, and a 1iroduct uf the immune system could be this factor. Cytokines are peptide mediators of the immune system . Tumor necrosis factor - (TNF- OC) is a cytokine derived from macrophages and lymphocytes and may cause endothelial cell injury in high levels and this lead to secretion of vasoactive substances , an increase in vascular permeability and intravascular coagulation All of these changes occur in pre - eclampsia.