الفهرس | Only 14 pages are availabe for public view |
Abstract A prospective cohort study was conducted on 80 severe head injured children admitted to the Neurosurgery Department at Mansoura Emergency Hospital from April 2003 to May 2006 for detecting cerebral blood flow changes in both Middle and Internal carotid arteries in severe peadiatric head trauma. Children with severe head trauma had mean age of 7.4 ±3.2years. boys constituted the majority of cases.motor vehicle accidents were the commonest cause of pediatric head trauma.Measuring the blood flow velocity by transcranial Doppler ultrasonography in severe pediatric head trauma showed a pattern of increase in the mean blood flow velocity on admission, day 3 reaching the peak on day 7 and thereafter, the flow velocity decreased on discharge in both middle cerebral and extracranial internal carotid artery. Post-traumatic vasospasm was diagnosed in twenty two cases out of eighty children with severe head trauma (27.5%) .Children with post-traumatic vasospasm who were given nimotope showed a lower mean blood flow velocity in middle cerebral arteries compared to the children with post-traumatic vasospasm who were not given the drug, However, the beneficial effect of nimotope on the outcome was not statistically significant. |