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العنوان
Immunoglobulins G and M in some haematologic malignancies and the effect of chemotherapy /
المؤلف
Shaban, Nagi mahmoud Samy.
هيئة الاعداد
باحث / ناجى محمود سامى شعبان؛
مشرف / فرج محمد فرج
مشرف / ساميه حواس
مشرف / ناجى محمود سامى شعبان؛
الموضوع
Haematologic malignancies - Immunoglobulins. Haematologic malignancies - Immunoglobulins.
تاريخ النشر
1985.
عدد الصفحات
235 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
جراحة
تاريخ الإجازة
1/1/1985
مكان الإجازة
جامعة المنصورة - كلية الطب - Department of General Medicine
الفهرس
Only 14 pages are availabe for public view

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from 273

Abstract

Among the consequences of established cancer, :l.mpairmen tof immune> COlllPe tence can be P~ticularly important. Lack of an appropriate immune response not only decreases resistance to infection, but may also faoilitate progressive tumour growth. Characteristic tmmunodefeoiency ’have been associated With different lympho reticul~ neoplasms which ~ise from cells that m~diate the immune response. Defects in immune func¬tion have also been associated With a varie~ of non lymphoid tumours When patients are eValuated prior to treatment. Surgery, radiotherapy, chemotherapy and hormonal manipulation may further compromise the ability of oanoer patients to respond immunologiCally to diff¬erent stimuli. Analysis of the complex interaction of tumour and treatment With the host-immune response has been enoOuraged by clinioal reports which link immuno¬oompetence with a favorable prognosis and immunodeteoi_ enay With a poor prognOSis. In addition, rational intervention with thel’apy designed to augment the speoifio immune response to infectious agents or to tumours will depend Ultimately on a precise understand_ ing of immune funotion in canoer patients before and during treatment.