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العنوان
Myelination of the spinal cord /
المؤلف
Sonpol, Hany Mosaad Ahmed.
هيئة الاعداد
باحث / هاني مسعد أحمد سنبل
مشرف / سميره لطفي عبدالهادي
مشرف / جمال أبوالفتوح محمد
مناقش / عادل عباس بندق
مناقش / إبراهيم لبيب عبدالله
الموضوع
Myelination. Spinal Cord-- blood supply. Spinal cord-- Anatomy and histology.
تاريخ النشر
2008.
عدد الصفحات
113 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الأجنة
تاريخ الإجازة
1/1/2008
مكان الإجازة
جامعة المنصورة - كلية الطب - Anatomy and Embryology
الفهرس
Only 14 pages are availabe for public view

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from 131

Abstract

Oligodendrocyte precursors develop through a series of stages that have been characterized by their distinct cell morphology and the expression of cell surface proteins. Lineage analysis has demonstrated that OPCs progress from bipolar, motile, and proliferative progenitors, through stellate, nonmotile, and proliferative pro-oligodendroblasts, into multipolar, nonmotile, and postmitotic oligodendrocytes.Each myelin sheath is composed of multiple segments of myelin, which are modified extensions of oligodendroglial cell processes. Each oligodendrocyte can contribute myelin to as many as 50 different axons. In addition to its importance in nerve impulse conduction, myelin may have a symbiotic relationship with the axon. Evidence suggested that myelin is synergistic with the developing axon and that the axonal cytoskeleton does not form properly in the absence of myelin.Three major domains (nodal environs) can be identified in the vicinity of the node of Ranvier (which are gaps in between myelinated segments of the nerve fibers): the node itself; the paranodal axoglial junction, and the juxtaparanodal region adjacent to the paranodes.