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Abstract The. presented work has been undertaken to investigate the effect of gastric ulcer on liver elycogen muscle glycogen, cardiac glycogen and blood glucose levels in rats Male albinorats were used for this experimental work. The rats were classified into the following groups Group I : included 15 normal rats fasted for 48 hours to act as control group Group II: included 15 fasted rats which are ex1ined iediately after induction of gastric stress ulcer by restrained technique Group III : included 15 normal rats. Group IV: included 15 rats which are exrunined after 48 On the day of work, the animals were anaesthetiz ed and their liver glycogen, muscle glycogen, cardiac glycogen, and blood glucose levels were estimated.Histopathological examination was made for gastric ulcer.The results obtained were tabulated and statistically analysed according to the student T test. The results can be summerised as follows:Fasting of rats for 48 hours led to a significant decrease in liver glycogen. Muscle glycogen, cardiac glycogen, blood glucose levels, on the other hand,were not statistically changed Immediately after induction of stress gastric ulcer, there was a marked decrease in liver glycogen muscle glycogen and cardiac glycogen. On the other hand, the blood glucose level was markedly increased After 48 hours of induction of stress gastric ulcer there was also a significant decrease in liver glycogen muscle glycogen, cardiac glycogen, and a significrut increase in blood glucose level Comparing the immediate gastric ulcer effect, prod uced by stress, and the effect resulted 48 hours after induction of gastric ulcer, it is apparent that liver glycogen and muscle glycogen were increased after 48hours of ulcer induction, due to removal of stress effectp compared to the immediate ulcer induction levels, |