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Abstract Background: the close association between the metabolic syndrome and obesity suggests that they share a common etiology postulated on insulin resistance. Obesity either total obesity measured by body mass index (BMI) or central obesity measured by waist circumference (WC) is a major component of the metabolic syndrome. Objective: To give an idea about what is the metabolic syndrome, its etiology, its components, how to predict or to diagnose, risk factors underlying or associated or developed. Also to get the relationship between the metabolic syndrome and body mass index and waist circumference as a diagnostic measures for obesity and predictors of morbidity and mortality. The prevalence of the metabolic syndrome among individuals within the various BMI categories both obese or non obese, clinical management and impact of weight loss on all the components of the metabolic syndrome will be also discussed. Conclusions: from the previous essay it is found that waist circumference is better than body mass index in the prediction and diagnosis of the metabolic syndrome, its morbidity, mortality, and its complications. Absence of obesity does not exclude the presence of the metabolic syndrome as it may be present in normal weight subjects. Weight reduction is strongly recommended especially in obese patients or even overweight as it improves all the components of the metabolic syndrome. |