الفهرس 
Introduction and Aim of the WorkOnly 14 pages are availabe for public view
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Abstract
Background: Nocturnal O2 desaturation (NOD) has long been recognized in COPD patients, who may spend 30% of sleep time with oxygen saturation < 90% mostly during REM sleep. Aim of Work: The aim of this work was to determine the rate of occurrence of nocturnal oxygen desaturators in COPD patients with or without OSAHS and to determine the predictors of OSAHS and nocturnal oxygen desaturators in COPD patients. Methods: This study was done on 50 patients of stable COPD (irreversible obstructive airway disease i.e. FEV1/FVC < 70%) and < 12% improvement in FEV1 expressed as percentage of predicted after inhalation of 2 agonists. All patients were subjected to the following: 1) Full history taking with stress on: -Epworth score. -Berlin questionnaire score. 2) Physical examination with stress on: -Neck circumference. -Body mass index (BMI). 3)Plain chest x-ray. 4) Laboratory tests. 5)Spirometric pulmonary function tests. 6)Calculation of BMI. 7)Polysomnography. RESULTS: According to Berlin questionnaire, there were 34 COPD patients (68%) with high risk to OSA and 16 COPD patients (32%) with low risk to OSA. The majority of COPD patients with AHI 5 (68.4%) were having the highest Berlin score (3) however the majority of COPD patients with AHI < 5 (83.3%) were having the lowest Berlin score (0). 38 patients (76%) of COPD patients were having AHI 5, 27 (54%) of COPD patients were having AHI 10, while 20 (40%) of COPD patients were having AHI 15 and lastly 19 (38%) of COPD patients were having AHI 20. Neck circumference, BMI, Epworth score and Berlin questionnaire score were significantly positively correlated with AHI (P = 0.001, 0.005, 0.000, 0.000 respectively). CONCLUSIONS: OSAHS and nocturnal oxygen desaturation were common in COPD patients with prevalence (76% and 64% respectively) in our study. Berlin questionnaire score and Epworth score were good subjective test for prediction of OSAHS and nocturnal oxygen desaturators. Spirometric pulmonary function tests was not considered a good predictor to OSAHS and nocturnal oxygen desaturation.