الفهرس 
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Abstract
Su1fonate esler Containing thiazolone derivative 1 was used as an
adaptabfe slarting material for the synthesis of new heterocyclic mono- ,Hi
- and tri fused ring systems that meight have extended and lor improved
antifunga1 activiiy. Thus ,when Compound ’1 was allowed to react with
hydrazine Ilydrale it gave a-Ihiobenzamido -P-[p -(benzene su!fonyloxy)
phenyIl~acrylic acid hydrazide 1.. Treatment of compound •Z with
sodium nitrite lInd lIet gave the corresponding acrylic add azide
derivative J. when the hltter product was extracted in boiling benzene, 4-
(benzenesuIfQnyJoxy phfnyl methyl) ~6- phenyl ~ 211 -1v3,5- thiadiazinone
derivative :I was formed in quantitative yield, (scheme-I),
Compound 1 reacted also witb activated nHrile to give bi~and tricyclic
fused ring systems. Thus renuxing compound 1 with malononifrile
Or {’{hyl cyanoacetate ofTorded the pyrono (3t2-d) tbiazole derivatives 1J!
a,b respectively (scheme-2). Treatment of the latter products with
hydrazine hydrate in ethanol gave the corresponding tricyclic fused ring
systems ~ 113 _ and lib respeclively (scheme ~ 3)~
Similar treatment of compmlDd (1) with 2-amtno-I.1,3 - tricyano
propene or 5-amino-4-cyano-3--cyanomethyl pyrazole (as activated nitrile
rtngents) yiddl’d also lite tricyclic fusro ring systems !j (sdH’me - 4) and
l.§ re,pedi.ely.