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Abstract Thirty patients of either sex were they were subject of this study. Their ages and body weight were ranged from 20-56 years and 55-90 kgms respectively. They were classified into three groups each was comprised of ten patients. They were transtrachelly injected with either normal saline (group I) or lidocaine 40 mg (group II) or lidocaine 40mg with morphine 1mg (group III) in a volume 2.5 ml. In all patients, anaesthesia was induced by thiopentone sodium 5 mg kg-1, intubation facilitated by suxamethonium 1 mgkg-1 and maintained by halothane 0.5% an N20-02 (2:1), muscle relaxant (vecuronium) and controlled ventilation. The heart rate, ECG changes, systolic and diastolic blood pressure were monitored 10 minutes before induction and every two minutes for 20 minutes after laryngoscopy and intubation There was significant reduction in heart rate, systolic, diastolic and mean blood pressure in lidocaine group and lidocainemorphine group compared to saline group but there was no significant changes between lidocaine group and lidocaine morphine group. Also, it was found that heart rate and systolic blood pressure significantly decreased in both groups compared to the preinduction values. |