الفهرس | Only 14 pages are availabe for public view |
Abstract Introduction: symptoms Gardnerella vaginalis is a bacterium that can normally live in the vagina of women without causing any sunless there is an imbalance in the vaginal environment Objectives: isolate, characterize and estimate the prevalence rate of Gardnerella vaginalis associated with various Gynaecological or/and Obstetric disorder and U.T.I cases. Patients and methods: This study comprised 175 patients, attending the Gynaecology and Obstetric Outpatient Clinic and Prenatal Care Unit, Mansoura University Hospital, during the period from August 2003 to October 2004.The age range was from 16 to 70 years, (mean age 43 years, S.D:(R+(B4). The patients were included into 3 groups. Results: Out of 175 patients, 35 (20%) patients had B.V with vaginal discharge, (9.1% pregnant and 10.9% nonpregnant). 65 (37.1%) had vaginal discharge without B.V, (19.4% pregnant and 17.7% nonpregnant), 15 (8.6%) preterm labour or premature rupture of membranes, 20 (11.4 %) Chorioamnionitis, 20 (11.4 %) endometritis and 20 (11.4%) had U.T.I ( 4% cases had B.V and 7.4% cases had no B.V).Out of 20 control subjects, 10 (50 %) were pregnant and 10 (50 %) were nonpregnant. 32% of cases complaining of vaginal discharge yielded positive clue cells in wet mount and 49%of cases presented with vaginal discharge yielded positive Gram smears. Out of 175 cases, 104 (59.4%) cases revealed growth of G. vaginalis, while 8 (40%) of 20 control subjects, recovered growth of G. vaginalis. Among 104 cases yielding +ve growth of G. vaginalis, 31(17.7%) had B.V with vaginal discharge ( 8%were pregnant and 9.7%were non pregnant}, 22(12.6%) cases had vaginal discharge without B.V (6.3% were pregnant and 6.3% were non pregnant );10 (5.7%) cases were in preterm labour ,14(8%)had chorioamnionitis ,13 (7.4) had endometritis ,and 14 (8%) had U.T.I , 4% of which had B.V. Conclusions: 1The presence of clue cells in wet mount examination is the single most reliable indicator of B.V.2Typical discharge is unreliable method of diagnosis having low sensitivity and specificity.3Fishy odor after addition of 10% KOH which is easily performed, can be used as part of the scheme used to diagnose bacterial vaginosis due to personal variation on perceiving the odor. 4Measuring pH of the vagina is useful, effective and inexpensive test for screening purposes. However, because of the high negative predictive value coupled with the act that it is an extremely simple and economical test to perform; pH testing of vaginal secretion remains a useful tool to rule out bacterial vaginosis and consequently G.vaginalis isolation. |