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العنوان
The study of sero­prevalence of hepatitis (e) virus immunoglobulin (igg) in patients with viral hepatitis /
المؤلف
Hammad, Shaimaa Hossein Mohammed Tharwat Hossein.
هيئة الاعداد
باحث / شيماء حسين محمد ثروت حسين
مشرف / فتحي عوض منصور
مشرف / أسامة سعد سلامة
مشرف / مايسة السيد زكي
الموضوع
Hepatitis, Viral. Hepatitis, Viral, Human - diagnosis. Hepatitis, Viral, Human - therapy.
تاريخ النشر
2004.
عدد الصفحات
178 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علوم النبات
تاريخ الإجازة
1/1/2004
مكان الإجازة
جامعة المنصورة - كلية العلوم - Department of Botany
الفهرس
Only 14 pages are availabe for public view

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Abstract

Hepatitis E virus is the major causative pathogen of enterically transmitted non­A, non­B hepatitis. HEV is a serious viral infection that occasionally cause large epidemics in developing countries. The living in rural area are exposed to high risk of HEV infection compared to urban population, whereas the presence of anti­HEV­IgG was significantly associated with consumption of common village water, oral therapy for schistosomiasis, and the high population density contributed to maintain this infection. The diagnosis of HEV infection is carried out routainly by serological assay for the detection of viral antibodies using Enzyme Linked Immunosorbent Assay (ELISA), which is sensitive and specific in detection of IgG and IgM antibodies to hepatitis E virus. The results for IgG anti­HEV were positive in 15 (34.1%) of 44 with hepatitis A virus(HAV­IgM), 12 (30%) of 40 with hepatitis B virus(HBs­Ag & HBe­Ag), 26 (40%) of 65 with hepatitis C virus(HCV­IgG), 5 (27.7%) of 18 with past­infection with HBs­Ab, and 2 (7.1%) of 28 with non­A, non­B, non­C hepatitis. The results for IgM anti­HEV were positive in 3 (3.3%) of 92 samples, as HEV­IgM was positive in 2 (20%) of 10 with hepatitis A virus (HAV­IgM) and in 1 (5.3%) of 19 with hepatitis B virus. On the light of the results in this study, there is a positive relationship between liver function levels, Blood picture count and infection with hepatitis E virus.