الفهرس | Only 14 pages are availabe for public view |
Abstract This work was done to study the correlation between RA and a possible microorganism inhabiting the urinary tract and microbiological identification of the bacteria isolated from the urine cultures of the studied groups. In this study, RA patients were divided into two groups; group?: active RA patients and group?: inactive RA patients according to clinical ground together with CRP and ESR values. Two control groups were involved in the study: Conrol group?: patients with symptoms of UTI. Control group IV: healthy subjects. Blood samples were taken from RA patients to measure CRP,RF and ESR values. Urine samples from RA patients and control groups were cultured by the quantitative culture method. Typing of urinary tract microorganisms in RA was done to correlate between a certain microorganism and the disease. This study revealed the following results: ” Increased frequency of isolation of P mirabilis from urine cultures of RA patients more than those from healthy subjects and patients with symptoms of urinary tract infection,this difference in the prevalence of P mirabilis is significant when RA patients compared to control groups. ” More frequant isolation of P mirabilis from urine cultures of active RA patients than from those of inactive RA patients with statistically significant difference. ” Bacterial count of P mirabilis isolates discovered from urine cultures of RA patients was usually insignificant(<105 cfu/ml) and pure. ” P mirabilis bacteruria of RA patients was usually asymptomatic. ” P mirabilis isolates discovered from urine cultures of RA patients were mostly sensitive to ciprofloxacin,norfloxacin and azteronam. ” No significant differernce in the antibiotic sensitivity pattern of P mirabilis isolates from RA patients and those from control groups. ” Genetic diversity in P mirabilis population found in the urinary tract of RA patients with no characteristic genotyping pattern in active RA that differentiate them from inactive RA. |