الفهرس | Only 14 pages are availabe for public view |
Abstract Background Aims: Although blood and blood product are safer than ever before, transfusion of allogenic blood and blood components still involve some risks (Weieskopf, 1996, Blajchman, 1998). In and effort to avoid such risks, acute normovolemic hemodilution (ANH) has become popular (Kreimeier and Messmer, 1996). Methods: Forty patients were randomally allocated into 4 groups according to type of fluid replacement and the anesthetic agent. Two groups received isoflurane for anesthesia in the first (Ic) HES was used as fluid replacement, in the second (Im) mixture of HES and Ringer solution was used for replacement. In other two groups halothane was used for anesthesia in group (Hc) HES was used only for replacement in the other group (Hm) mixture of HES and Ringer solution was used for replacement. They were monitored for hemodynamic parameters and oxygenation by insertion of a pulmonary artery catheter. The readings of hemodynamics and oxygenation were obtained before withdrawal for basal data, then immediately after hemodilution and then every half an hour intraoperative. Results: The readings of hemodynamics and oxygenation were obtained before withdrawal for basal data, then immediately after hemodilution and then every half an hour intraoperative (after induction of anesthesia) then patients received their own blood and the readings were obtained for 3 hours after reinfusion. The mean of 4 intraoperative readings and after reinfusion 4 readings were represent in tables. Conclusion: The use of mixture of colloid and crystalloid provides accepted degree of stability of the hemodynamic parameters and oxygenation variables with accepted degree of prolongation in the coagulation times (PT and APTT) and accepted amounts of blood loss. |