الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Weaning trials are performed to assess the readiness of anically ventilated patients to sustain spontaneous ventilation. The critical time for patients with chronic obstructive pulmonary disease D) mechanically ventilated for acute respiratory failure (ARF) is the g period. The resumption of spontaneous breathing after mechanical lation imposes several loads on the cardiorespiratory system: Venous n increases, thus increasing ventricular preload , left ventricular load increases ,and total body oxygen consumption increases by ~ y 15 to 20%. The prevalence of invasive monitors in the intensive care unit (ICU) g. Easily overlooked and often not considered is that much of the e information can also be obtained by non invasive means 7herefore,- this study was planned to assess cardiopulmonary changes g weaning of mechanically ventilated COPD patients by non invasive . toring methods and to assess its impact on the weaning outcome, and the same time to find out the best modes of weaning in such patients. This study included 40 COPD male patients mechanically ntilated for acute on top of chronic respiratory failure with mean age of 1.45 ± 9.17 years. They were divided into four groups according to the ode of weaning SIMV group (1 I patients),. PSV group (I l patients), T- ece group (9 patients ) and CPAP group (9 patients), and subsequently ubdivided into successful (31 patients) and failed ( 9 patients) groups ccording to the outcome of weaning Allpattents were subjected to thefollowing ~l Thorough history taking (from relatives) and clinical examination Plain X - ray chest AP view ,3. Complete laboratory investigations with special stress on Arterial. blood gases, preventilation, for 24 hour at the onset of ventilation, during the weaning period and for 24 hour within one.