الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Hyaline membrane disease is a serious disease affecting newborns and limited to the early days of life. It is a very important cause of severe respir¬atory distress in infants ~fter birth and unless treat¬ment startes, the infant will die from respiratory and metabolic acidaemia • It is characterised by diff¬iculty in breathing, chest retraction, respiratory grunting, tachypnea and cyanosis. Many factors pred¬ispose to the disease as short gestation, foetal distress, Rhesus incompatibility, diabetes mellitus of the mother or caesarean section. An important obs¬ervation is that not all the newborns under these cond¬itions develop HMD. Also the disease is more common in twins and recently it is postulated that familial factors may play a role in the pathogenesis of the dis¬ease. This stimulated us to do the present work to detect 8 possible genetic control of the disease. Up till now , no specific genetic marker is char¬acteristic for HMD • As striking relationship have been found between HLA-antigens and many diseases, the pres¬entwork was undertaken to look for any association between HMD and certain alleles of the HLA-A,B,C and DR.