الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Phenylketonuria (PKU) is an inherited metabolic disease, carried through a recessiv? gene involved in the absence or partial inhibition of the enzyme phenylalatine hydroxylase (liver enzyme), and consequently interrupt the conversion of amino e acid, tyrosine resulting in amino acid imbalance in fetal tissues retarding cell proliferation and interfere with the development of gonadal germ cells either directly or through its adverse effects on thyroid hormones. In the postnatal youngs of PKU mother, the seminiferous tubules attained a considerable atrophy. The lumina of the tubules were occluded or filled with eosinophilic cellular debris as shown in the postnatal youngs of PKU mother. In postnatal youngs of PKU mother, the ovaries possessed different phases of atrophied and degenerated oocytes of the ovarian follicles.