الفهرس 
ىOnly 14 pages are availabe for public view
 |  | from | 123 |  |  |
| | | from | 123 | | |
Abstract
”This study aimed to compare the antibacterial effect of Salvadora persica (Miswak), and sodium hypochlorite, as root canal irrigating solutions against Enterococcus faecalis (E. faecalis) bacteria, and to compare their effects on microhardness and bond strength to root dentin. Seventy-five extracted single-rooted mandibular premolars human teeth with closed apex were included in this study. Initially, the teeth were cleaned, prepared, and then disinfected. E. faecalis were inoculated in the root canals which were divided randomly into five equal groups according to the type of irrigant used [group (1): saline (-ve control), group (2): 5.25% NaOCl (+ve control), group (3): 10% Miswak, group (4): 15% Miswak and group (5): 20% Miswak]. Specimens from each group were subjected to microbiological assessment at two-time points; before and after root canal treatment with different irrigating solutions to detect viable bacterial cells using minimal inhibitory concentration (MIC) and agar diffusion test. The specimens were embedded in acrylic resin, except for the cervical surface and positioned in a vickers microhardness tester (Future-Tech Corp FM-700, Tokyo, Japan) to detect root canal dentin microhardness, then assess the bond strength of root canal material to dentin after irrigation, obturation and the push-out test were applied. The collected data were then statistically compared to detect differences between the tested root canal irrigants. No significant difference between the groups before treatment. After using tested irrigant solutions, 20% Miswak and sodium hypochlorite showed a significant antibacterial effect better than 10%, 15% Miswak, and saline. Only the sodium hypochlorite group showed a significant decrease in root canal dentin microhardness after the treatment and is preferred over miswak irrigant, concerning their effect on bond strength between the sealer and dentin. Within the limitation of the present study, the antibacterial effect against Enterococcus faecalis of 20% Miswak is comparable to 5.25% NaOCl. Regarding its use as a root canal irrigating solution, 20% Miswak does not affect the dentin microhardness negatively, but showed a lower value of push-out bond strength. Regarding antibacterial and microhardness effects, 20% Miswak can be used as an effective herbal alternative for NaOCl irrigation solution.”