الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Paracetamol is a widely used non-prescribed medication worldwide for pain and fever. Paracetamol poisoning and paracetamol-induced hepatotoxicity constitute major public health problems both nationally and globally. Since early detection and treatment can greatly lower morbidity and mortality, it is critical to identify cases of paracetamol overdose.
This research aimed to study the prevalence of paracetamol poisoning, detect the incidence of hepatotoxicity, and evaluate the severity of poisoning among patients with acute paracetamol toxicity.
The study was conducted on 75 patients with acute paracetamol overdose who were admitted to Alexandria Poison Center for 6 months from the first of June 2023 till the end of December 2023 after applying the inclusion and exclusion criteria. After obtaining informed consent from all patients, the patients or their legal guardians were interviewed. The patients were clinically examined, laboratory investigations were performed and the patients were managed according to therapeutic protocol. The data were recorded in a specially designed sheet. Poison Severity Score (PSS) was employed for determination of the cases’ severity.