الفهرس 
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Abstract
The aim of this thesis is to synthesize new compounds derived from 1-cyanoacetyl piperidine and study their effect in two fields:
1- Supercritical carbon dioxide (scCO2) has been suggested as a good substitution to environmentally harmful water-based tincturing. The present study describes the successful synthesis of some biologically active dispersion tinctures for supercritical carbon dioxide tincturing of polyester fabric. The coupling of 1-cyanoacetylpiperidine (1) with the diazonium salt of aryl amine derivatives (2a–d) produced 1-((aryl diazenyl) cyanoacetyl piperidines (3a–d). To create the derivatives of 4-(phenyl diazenyl)-5-(piperidin-1-yl)-1H-pyrazol-3-amine (5a), the propanenitriles (3a–d) were condensed with hydrazine hydrate. The MS, IR, and NMR spectra were used to describe the novel dyes. The antibacterial test against microorganisms included Escherichia coli, Pseudomonas aeruginosa, Bacillus cereus, and Staphylococcus aureus revealed that some of the compounds (3a–d) and (4a–d) had impressive antibacterial capabilities against the researched gram +ve and -ve bacteria. For eight dyestuffs, the dyeability, color strength, and color fastness of the tincturing process were
2- The N-acetyl piperidine derivatives 6, 8, 10, and 11 were synthesized and exhibited antifungal activities against five fungal species of wood-decay basidiomycetes and two Ascomycetes-plant pathogens. According to the results of the antifungal activity test the compounds showed excellent inhibition behavior.