الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Endometrial cancer is ranked as the sixth most common cancer in women worldwide. By 2030, the incidence of endometrial cancer is projected to increase by 55% over the number of cases recorded in 2010 in the USA owing to an ageing population and escalating rates of obesity. Women with endometrial cancer mostly present either with postmenopausal bleeding or peri-menopausal abnormal bleeding. A two dimensional (2D) trans-vaginal sonography has long been the first line modality in endometrial evaluation. Potential screening modalities for endometrial cancer include endometrial sampling through endometrial aspiration biopsy, dilatation and curettage and hysterectomy have been used for the evaluation of endometrial pathology in patients with PMB. Therefore, the aim of this work was to assess the accuracy of the measurements of three-dimensional ultrasound (endometrial thickness, volume) and power Doppler indices as a predictor of the occurrence of endometrial cancer in women with postmenopausal bleeding and to correlate the results with the histopathological study of the endometrial biopsies. This prospective clinical study was carried out upon 100 postmenopausal patients (amenorrhea for 1 year) women complaining of abnormal uterine bleeding. Patients were subjected to thorough general, abdominal, prevaginal pelvic & speculum examinations. Ultrasound examination was done by 2DUS to measure ET, Also 3D ultrasound examination was done to measure ET & EV. Three-dimensional (3D) power Doppler was also used for measuring the vascular indices of endometrial blood flow. Endometrial biopsy was taken from all studied cases by dilatation and curettage or hysterectomy.