الفهرس 
Introduction & Aim of the workOnly 14 pages are availabe for public view
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Abstract
Idiopathic pulmonary fibrosis is scarring of the lung tissue, namely the interstitial spaces, over time and for no apparent reason and after ruling out other potential causes, the diagnosis of this condition can be made when either a radiological pattern of UIP is seen in a high-resolution computed axial tomography (HRCT) or a histological pattern of UIP in a lung biopsy sample.
Complications such as pulmonary hypertension (PH) are common in patients with idiopathic pulmonary fibrosis (IPF). The prognosis is especially poor for people who have pulmonary hypertension (PH) with idiopathic pulmonary fibrosis (IPF).
The mean pulmonary arterial pressure (mPAP) measurement using transthoracic echocardiographic is combined to HRCT in cases of idiopathic pulmonary arterial hypertension , By combining the two approaches, we can receive more complete and accurate results, which might lead to a more precise PH diagnosis. The researchers set out to determine how well a high-resolution computed tomography scoring system worked in conjunction with echocardiography to assess the severity of idiopathic pulmonary fibrosis.
Forty people, with an average age of 59.5, who had been diagnosed with IPF via HRCT were included in this study. With a female-to-male ratio of 1.6:1, 62.5% of the inhabitants were female. This indicates that IPF is more common in females than in males. According to the NYHA system, most of the people showed signs of dyspnea of grade II and III.
The average total HRCT score was 20.2 points , the lower lung zone was highly affected by IPF than the upper and intermediate lung zones. Pulmonary hypertension (PH) was likely present due to the average pulmonary artery systolic pressure (PASP) value of 61 mmHg. There was also a positive and statistically significant correlation between PASP and the total lung zone HRCT score.
The total lung zone HRCT score is inversely related to the FEV1/FVC ratio. In addition, the correlation between FVC and HRCT total score was -0.86, which is a strong negative connection.
Po2, SPO2, FVC, and FEV1/FVC were found to have a statistically significant negative association with PASP.
We found a somewhat negative correlation between participants’ pulmonary artery systolic pressure (PASP) and their 6-minute walk test (6MWT) distance.
A strong and direct correlation was found between dyspnea severity and pulmonary artery systolic pressure (PASP). Additionally, PASP and partial pressure of carbon dioxide (PCO2) were shown to have a somewhat favourable relationship.
Several other factors have statistically significant association with the HRCT total score. The overall score on the HRCT is positively correlated with age, PASP, PCO2, dyspnea grade, and PCO2. The overall score on the HRCT is negatively correlated with factors including 6MWT, PO2, and SPO2.
Patients with idiopathic pulmonary fibrosis can be more accurately diagnosed with disease severity utilising a combination of high-resolution computed tomography score and echocardiography measurements of pulmonary artery systolic pressure.