الفهرس 
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Abstract
Myopia is a common refractive error characterized by the elongation of the
eyeball, resulting in light being focused in front of the retina instead of on it. While
myopia is generally not considered a risk factor for glaucoma, recent studies have
suggested that higher degrees of myopia may increase the risk of developing glaucoma.
A meta-analysis of 19 studies found that individuals with high myopia (greater
than -6.00 diopters) had a significantly higher risk of developing glaucoma compared
to those with low myopia or no myopia. Additionally, a study of nearly 4,000 Japanese
individuals found that those with high myopia had a higher prevalence of glaucoma
compared to those without myopia.
The exact mechanism behind the association between myopia and glaucoma is
still unclear, but it is thought that the elongation of the eyeball in myopia may lead to
changes in the optic nerve head and increased susceptibility to damage. Additionally,
the presence of myopia may make it more difficult to accurately diagnose glaucoma, as
the characteristic changes in the optic nerve head may be more difficult to distinguish
from those associated with myopia.
This study aim to detect the risk of glaucoma in relation to degree of myopia
This study aims to investigate the risk of developing open-angle glaucoma (OAG)
in relation to the degree of myopia in 48 patients with myopia. Inclusion criteria for
participants are patients with myopia between the ages of 18 to 40 years old, with OAG
as the outcome measure. Exclusion criteria are patients with age below 18 or more than
40, previous refractive surgery, secondary or angle-closure glaucoma, or other eye
diseases that cause glaucoma. Patients will be examined for axial length of the eye, IOP,
corneal thickness, and OCT optic disc to detect the risk of OAG in myopic patients. The
examination will include visual acuity, best-corrected visual acuity, evaluation of IOP
using air puff tonometer, fundus examination with indirect ophthalmoscopy and slit
lamp biomicroscopy, corneal thickness, and OCT optic disc. A total of 96 eyes will be
Summary
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studied, with mild myopia defined as 0D to -1.5D, moderate myopia as -1.5D to -6D,
and high myopia as -6D or more. An informed written consent will be obtained from
each participant, and eligible patients will be enrolled in the study according to defined
inclusion and exclusion criteria.
This study investigated the relationship between myopia and glaucoma risk
among 48 patients with myopia. The results showed no significant difference in sex
distribution across different degrees of myopia, but a higher risk of glaucoma in patients
with higher degrees of myopia. In the mild myopia group, there were no significant
differences between left and right eyes except for the thickness of the superior and
inferior NFL. However, in the moderate myopia group, the spherical equivalent was
significantly higher, the average NFL thickness was lower, and the C/D ratio was larger
compared to the mild myopia group, indicating a higher risk of glaucoma development.
In the severe myopia group, there was a significant increase in the negative spherical
equivalent and decrease in the NFL measurements, suggesting a progression of the
condition. Additionally, axial length of the eye increased with severity, with a
statistically significant difference between mild and moderate, moderate and severe
groups. The study also found that the severity of glaucoma was significantly associated
with the ONH analysis parameters, specifically the C/D ratio and C/D V. ratio.