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Abstract This was a cross-sectional hospital-based study to evaluate the impact of the COVID-19 pandemic on pediatric vaccinations compliance among children attending to Assiut University Children Hospital and to assess the general health profile of studied children. The study was done on children up to 2 years at duration of 1 year (from 5/2021 to 6/2022). All cases in the study were subjected to: o Full clinical history including birth weight, nutritional status, gender, gestational age, weight at time of vaccination. o Information regarding immunization and practices were collected by using a semi- structured questionnaire: The questionnaire consisted of 3 sections: - The first section consisted of items to explore socio-demographic characteristics of respondents (age, family number, father’s education, father’s job, mother’s education, mother’s job). Socio-economic level of the families of the studied children was determined by using the socioeconomic status scale developed by El-Gilany et al. El-Gilany scale used to assess socio-demographic characteristics includes: seven domains, education and culture for both (husband and wife), occupation, family, economic status, family possessions, home sanitation and health care domain. - The second section contained items to assess the data of the child (age, sex, religion, residence, number of brothers and sisters, order of the child among living siblings, Mode of delivery, Place of delivery). Moreover, data regarding Maternal and neonatal delivery related complications need for intubation, neonatal problems, feeding type and numbers of twins’ pregnancy were obtained. - The third section contained COVID-19 infection among the studied children including symptoms of COVID-19 infection, hospital admission, family member infected with COVID-19 infection, acceptance of vaccination during the pandemic, precautionary measures at sites of vaccination and general vaccinations received among the studied children. It was found that 45.7% of the studied children had complete vaccinations and this are significantly associated with younger child age, father education, high social class and presence of neonatal problems. Regarding the prevalence of nutritional status, it was revealed that 88.8% of children had normal weight-for-age, 85.3% of children had normal height-for-age and 89.7% of children had normal weight-for-height. By comparison the COVID-19 and not COVID-19 patients, there is insignificant difference between both groups as regard height-for-age, weight-for-height and weight-for-age. However, among the COVID-19 group, no cases were stunted or underweight and 20.0% were wasted. But among the other group, 84.7% were stunted, 9.9% were wasted and 11.7% were under-weigh. |