الفهرس 
INTRODUCTION AND RATIONALEOnly 14 pages are availabe for public view
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Abstract
Non-alcoholic fatty liver disease has become one of the most prevalent liver diseases worldwide and is noticed to affect 20%-45% of the general population and 60%-75% of obese people. It represents a series of conditions from simple steatosis to non-alcoholic steatohepatitis and cirrhosis. NAFLD is a complex disease affected by different pathways, involving environmental, genetic, and metabolic factors and recent investigations have focused on the microbiota of the gut, as an etiology for NAFLD.
Helicobacter pylori is a gram-negative, microaerophilic, bacteria that colonize the gastric wall. The H. pylori infection prevalence is about 30% in the developed countries and up to 80% in developing countries (Wessler et al., 2017). H. pylori is thought to have a role in the pathogenesis of NAFLD by stimulating the release of proinflammatory cytokines, increasing insulin resistance, and increasing intestinal permeability (Li et al., 2017).
Specific studies regarding the association between H. pylori infection and NAFLD are increasing. Some of them found a relationship between H. pylori infection and NAFLD, while others found that H. pylori infection isn’t related to NAFLD.
We performed our study to analyze the possible association between H. pylori infection and NAFLD frequency rates, and to determine this relationship, and to compare the characteristics of Helicobacter pylori positive and Helicobacter pylori negative non-alcoholic fatty liver disease.
We performed our study on 217 participants who did abdominal ultrasound for different indications. The subjects were tested for H. pylori by detection of H. pylori antibody IgG in the serum by enzyme-linked