الفهرس 
Introduction and rationaleOnly 14 pages are availabe for public view
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Abstract
Hemodialysis patients carry a large burden of cardiovascular disease, accounting for up to 41% of deaths, of which half are ascribed to sudden SCD. As a result, the most onerous is the high risk of SCD. Within this complex disease category, it is likely that a large proportion of these events are related to development of fatal cardiac arrhythmia.
The pathophysiology of SCD is thought to result from the combination of a vulnerable myocardium and an acute pro-arrhythmic trigger that leads to a terminal arrhythmia. Approximately two thirds of the cardiac deaths are consistently attributed to arrhythmias.
Some of the risk factors of cardiac arrhythmias, include dialysate composition, timing, and frequency, they are modifiable and hence provide an option for interventions to potentially reduce SCD. In addition, there might be a relationship between the timing of dialysis and SCD that tends to occur during the long inter-dialytic period. Furthermore, intradialytic hypotension is a common complication of HD and is associated with development of reduced myocardial perfusion, a potential risk factor for arrhythmia.
The type of fatal arrhythmia responsible for SCD differs between before and after HD. Sudden cardiac arrest from ventricular fibrillation was more often