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Abstract The aim of study was to evaluate the prevalence of post-cesarean scar niche in patients with post Cesarean section surgical site infection as Skin and subcutaneous infections, Gapped wound, Pus collection and Exploration on collection by 2D saline infusion sonohysterography. A prospective observational study was conducted on 100 women at department of gynecology in Minia university hospital for follow up after CS SSI. The study was initiated during the period from June, 2022 to June, 2023. The main results of the study revealed that: The mean age was 33.2 ± 3.5, 35% had ideal BMI, 50% were overweight, 15% were underweight. The mean Parity was 2.5 ± 0.7. 48% were urban. The mean Gestational age at delivery was 39 ± 0.7. The mean fetal weight was 2567 ± 220. 48% were Elective. 52% were Emergency. 61% had Specialist, 39% had Consultant. 12% had Preeclampsia, 17% had ROM, 16% had GDM and 11% had APHG. 10% had DM, 13% had HTN and 8% had SLE. 55% had Superficial and 45% had Deep SSI. The mean Onset after CS was 7 ± 2. 84% had niche, the mean Length (cm) was 15±2.1, the mean Depth (cm) was 6.22 ± 5.21 and Width (cm). 71% had Triangular niche, 26% had Semicircular niche and 3% had Droplet. There was a significant association between niches with residence. There was a significant association between niche and BMI. There was no significant association between niche and parity. There was a significant association between niche and type of CS. There was a significant association between niche and surgeon either consultant or specialist. There was significant association between type of SSI and Length. There were significant association between type of SSI and Depth and Width]. Niche prevalence was significantly higher among superficial compared to deep (90.9% vs 75.6%). There were non-significant association between type of SSI and obstetric and medical history. 45% were positive as Marked Pus Collection There was no significant association between niche and marked pus collection. There was no significant association between niche and Management among marked pus collection patients. There was no significant association between niche and scar in patients managed by abdominal exploration among marked pus collection. |