الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Hirschsprung’s Disease (HD) is a congenital malformation that occurs when part or all of the large intestine or antecedent parts of the gastrointestinal tract have no gangalion cells in the myenteric and submucosal plexuses and therefore cannot function normally. The affected segment of the colon cannot relax and pass stool through the colon, creating an obstruction.
Hirschsprung’s disease occurs in 1 out of every 5,000 live births. it is one of the most common causes of functional intestinal obstruction in pediatrics. With male-to-female ratio is about 4:1 overall, but approaches 1:1 in long-segment Hirschsprung’s disease. the etiology is multifactorial, with genetics
playing a major role.