الفهرس | Only 14 pages are availabe for public view |
Abstract Background: STEMI is the most serious presentation of atherosclerotic CAD carrying the most hazardous consequences. STEMI is caused by occlusion of a major coronary artery and primary PCI is the recommended reperfusion therapy over fibrinolysis if performed by an experienced team as soon as possible. Myocardial infarction makes significant changes in composition, shape, and contractile function of myocardium. Especially left ventricle which is the major contributor to the contractile function of the heart, so it affects the systolic and diastolic functions of the heart. Objective: To study the dynamic changes of left ventricular global longitudinal strain and diastolic function parameters in patients undergoing primary percutaneous coronary intervention with TIMI flow grade III after anterior STEMI Methods: This study is a prospective observational study that was conducted at Ain Shams university hospitals, in the time interval from October 2022 till June 2023. A total of 100 Patients diagnosed with anterior STEMI Results: Our study showed significant improvement in LV systolic function and GLS after PCI during the follow-up and showed significant improvement in diastolic function parameters after PCI during the follow-up. Univariate logistic regression analysis for factors associated with poor outcome on GLS included Age > 53, DM, Chest pain to door > 7 and CK-total > 4356. Conclusion: In the present study we found Our study showed significant improvement in LV systolic function, diastolic function parameters and GLS after PCI during the follow-up. There is poor outcome on GLS when Age > 53, DM, Chest pain to door > 7 and CK-total > 4356. Finally Chest pain to door > 7 was identified to be the most dependent predictors of GLS reduction at follow-up. |