الفهرس 
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Abstract
Summary
Type 1 diabetes (T1D), because of the rising incidence, remains a challenge. With time, systemic consequences such as anemia may develop in children with T1D. Anemia in T1D may have a complex, multifactorial background.However there are few works that investigate iron deficiencyanaemia in children with type 1 diabetes.
Hence we conduct this case control study included110 children, fifty-five of them with type 1 diabetes mellitus following up at the outpatient’s paediatric endocrinology clinic, paediatric department, Beni-Suef university hospital and fifty-five healthy control children to investigate about iron Deficiency anemia in Children with Type 1 Diabetes Mellitus and compare it with healthy controls.
All patientsunderwent complete history taking, full physical examination and investigations including complete blood count, serum ferritin, serum iron, HbA1C, fasting blood sugar and 2-hour postprandial blood sugar.
We found that prevalence of anemia among Children with Type 1 Diabetes was 29.1% while among healthy controls was 12.7%. Anemia was significantly more prevalent among type 1 Diabetes than controls.
When comparing between children with type 1 diabetes and controls, we found that mean values of Hb, RBC, MCV, MCHC, MCH, serum iron, serum ferritin were significantly lower in diabetic children than controls.HBA1c mean values were significantly higher among children with type 1 diabetes than healthy controls.
To compare between different duration of type 1 diabetes, patients were classified into 4 groups; group A: 0–1 y (n=12), group B: 1–3 (n=11), group C: 4–6 y (n=24) while group D: > 6 y ( n=8). We found a significant difference regarding Hb and MCV mean values among children with type 1 diabetes in comparison with duration of diabetes as the lower mean values were among over 6 years diagnosed children.
Mean values of Hb, MCV, serum iron, serum ferritin were significantly lowerinanaemic diabetic children (whose ferritin <15) than those non anaemic diabetic children (whose ferritin >15).We also found that mean values of BMI were significantly lower among anaemic-diabetic children with serum ferritin <15 than non anaemic children with serum ferritin >15.Moreover HBA1c mean values was significantly higher among anaemic diabetic children (whose ferritin <15) than those non anaemic diabetic children (whose ferritin >15). There was also a moderate negative correlation between HB and HBA1c.