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Abstract
To identify whether or not junctional zone thickness should be considered as afactor in the determination of success / failure rates in assisted reproduction techniques.Design Prospective clinical imaging study. Setting In Vitro Fertilization Unit at Kasr Al Ainy University Hospitals, Cairo, Egypt Patient(s)100 patients aged 21-40 years old, diagnosed as primary or secondary infertility due to the following causes of infertility; ( Pelvic Inflammatory disease, dysovulation , tubal infertility, unexplained infertility, combined infertility or due to male factor ). These patients are then assigned to receive fertility treatment (ovulation induction, ICSI, intrauterine insemination and IVF). They undergo a 3D vaginal ultrasound before treatment to measure the junctional zone thickness and followed up after treatment to determine the rate of implantation. Intervention(s) All patients will undergo 3D ultrasound to measure the thickness of the junctional zone at day 21 of the cycle. 25 participating patients will undergo ICSI, 25 patients IUI, the rest will be treated by induction with clomidecitrate.Main Outcome Measure(s) Junctional zone thickness and the pregnancy rate.ResultsThe junctional zone thickness was relatively thinner in patients who became pregnant than in non pregnant patients. The average junctional zone value of 0.27 cm was the cutoff point as determined by the results