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Abstract
Objective: Term labor is associated with global thinning of the myometrium. We hypothesized that a thickened myometrium at the time of preterm premature rupture of membranes (PPROM) predicts less myometrial wall stress and, consequently, a longer latency interval. Study design: Myometrial thickness was measured prospectively in 100 pregnant women enrolled in the following groups: preterm premature rupture of membranes (PPROM), preterm non-labor control group (P-CTR), and term non-labor control (T-CTR). All preterm premature rupture of membranes (PPROM) women had oligohydramnios. Myometrial thickness was measured ultrasonographically at the midanterior, fundal, posterior, and lower uterine segment wall in cases and controls. Conclusion: Significant thickening of the anterior and fundal walls of the uterus follows preterm premature rupture of membranes (PPROM). A thick myometrium in non-laboring patients with PPROMis associated with longer latency interval. Sonographic evaluation of MT may represent an alternative clinical tool for the prediction of a short latency interval in women with preterm premature rupture of membranes (PPROM).