الفهرس يوجد فقط 14 صفحة متاحة للعرض العام
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المستخلص
Background:Previous studies have shown that high HbA1c concentrations considered within the {u2018}normal range{u2019} may detect individuals with increased propensity for developing type 2 diabetes mellitus in the near future. Available information has also suggested that in the general population, high HbA1c concentrations may detect individuals at higher risk for cardiovascular mortality. However, little is known whether a non- diabetic subject with a family history of diabetes is at high risk for vascular damage or not. The aim of the present work was to evaluate the arterial status of healthy offspring of diabetic patients. Conclusions:This study demonstrated that the CCA IMT and aortic stiffness index are significantly higher in subjects with parental history of diabetes compared with subjects without parental history of diabetes. Therefore, these findings suggest that glycemic control might have a pathophysiological relevance in the development of vascular disease, even in individuals without diabetes