الفهرس Only 14 pages are availabe for public view
 |  | from | 119 |  |  |
| | | from | 119 | | |
Abstract
Background:The thalassemia syndromes represent the most common causes of ineffective erythropoiesis . The increased but ineffective erythropoiesis resulting in tissue iron overload induces numerous endocrine diseases, hepatic cirrhosis, cardiac failure and even death . Objectives: To study GDF15 levels in Ý- thalassemia major patients and to correlate its level to their iron status and different clinical and laboratory disease parameters. Conclusion:GDF15 level in our study represent a first step for its use as biomarker in thalassemia patients although future studies may be needed before its routine use