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العنوان
Expression of intercellular adhesion molecule - 1 (ICAM -1) in patients with hepatocellular carcinoma /
الناشر
Somia Saad Abdelshafi Mohemed ,
المؤلف
Somia Saad Abdelshafi Mohemed
هيئة الاعداد
باحث / Somia Saad Abdelshafi Mohemed
مشرف / Amr Saad Mohamed
مشرف / Mohamed Said Abdelaziz
مشرف / Amal Ahmed Mohamed
تاريخ النشر
2014
عدد الصفحات
123 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Biochemistry
تاريخ الإجازة
21/4/2015
مكان الإجازة
جامعة القاهرة - كلية العلوم - Biochemistry
الفهرس
Only 14 pages are availabe for public view

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from 155

Abstract

Hepatocellular carcinoma (HCC), the third most common cause of death from cancer worldwide which accounts for 80% - 90% of primary liver cancer, is characterized by a very poor prognosis . Outcome of Hepatocellular carcinoma depends mainly on its early diagnosis. Serum Ü-fetoprotein (AFP) is the only marker that has been widely used for screening and diagnosis of HCCs. However, development of false-negative or false-positive rates with (AFP) was as high as 30% - 40% for patients with small hepatocellular carcinomas. Besides these features, a number of biological markers including cytokines and growth factors have been demonstrated to be increased in the sera of patients with HCC and may be associated with a poor prognosis. Thus the identification of novel biochemical markers for HCC remains an important goal for many laboratories around the world. Intercellular adhesion molecule {u2013} 1( ICAM - 1) is one of the positive prognostic markers secreted, abundantly in several human tumors including HCC