الفهرس 
Trichinella spiralisOnly 14 pages are availabe for public view
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Abstract
Trichinosis is a widespread zoonosis, which is acquired through ingestion of undercooked pork and its products containing infective encysted larvae of Trichinella spp. Most human infections are accidental and caused by Trichinella spiralis. Through T. spiralis life cycle, the newborn larvae migrate and invade the muscle cell inducing a remarkable series of physiological changes causing transformation of this fully differentiated muscle cell into a nurse cell. Regarding to the treatment, anthelminthics such as mebendazole and albendazole are commonly used to treat human trichinellosis. However, none of these drugs have a full effect against the encysted or newborn larvae of T. spiralis because of their low bioavailability, and their side effects on the human. Nowadays, the production of anthelmintic drugs from some plant extracts has a major interest and thus, an effective therapy with new improved drugs of plant origin is needed.