الفهرس 
Title : A retrospective cross sectional study in educational hospitals and institutions in cairo governorate
AbatractOnly 14 pages are availabe for public view
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Abstract
To define the prevalence rate and epidemiological characteristics of the metastatic tumors to the jaw bone that were diagnosed histopathologically and immunohistochemically, if available, over a period of ten years (from 2010 to 2019) in educational hospitals and institutions in Cairo Governorate.
Methodology:A retrospective patient record files in the pathology diagnostic service at educational hospitals and institutions in Cairo Governorate were searched manually and electronically for cases of metastatic jaw tumors. Clinical and pathological reports of included cases were revised and data about patients’ age, sex, and site of primary and metastatic tumor, clinical presentation of metastasis, radiographic features, histopathologic diagnosis and list of the used immunohistochemical stains in the biopsied specimen from the jaw were collected and analyzed.
Results: A total of 254 patients with malignant tumors of the jaws, only 21 (8.3%) cases were diagnosed with metastatic tumors of the jaws, only 11 patients (52.3%) had been diagnosed previously and were being treated for a primary tumor. Most metastatic tumors to jaws were found in patients in their fifth to sixth decades. The mean age of the patients at diagnosis was 57.61 years and almost equally distributed between male 11 cases (52.3%) and female 10 cases (47.61%) with
male to female ratio 1.1:1. The mandible was more involved than the maxilla comprising 17 (81%) and 4 (19%) sites respectivelywith mandible to maxilla ratio 4:1.
The most clinical presentation was rapidly progressing swelling and pain. It showed mostly an expansile osteolytic area with ill-defined margins and cortical destruction in radiographic examination. The most common primary sites, for men were the liver five cases (45.5%), followed by thyroid two cases (18.2%) and lung two cases (18.2%) while for women, the breast and the liver came first with three cases each (30%) followed by thyroid gland two cases (20%). The predominant histopathological types were hepatocellular carcinoma followed by thyroid carcinoma then ductal carcinoma of the breast and adenocarcinoma.