الفهرس 
Assessment of implementing nano technology in the irrigation protocol of one step revascularization for necrotic mature teeth: Randomized clinical trial
ABSTRACTOnly 14 pages are availabe for public view
 |  | from | 148 |  |  |
| | | from | 148 | | |
Abstract
Aim:The present study aimed to observe in patients with necrotic teeth with apical periodontitis, if the use of Propolis and Nano-propolis as final endodontic irrigants, will reduce postoperative pain and affect the success of revascularization associated with PRF or not.
Methodology: Eighty-four patients with necrotic maxillary anterior teeth with apical periodontitis and a periapical lesion were recruited from the outpatient clinic of the Endodontic Department -Faculty of. Dentistry– Cairo University. Patients were screened for eligibility through obtaining medical and dental histories of the patients together with clinical diagnosis. Patients were then referred to do a preoperative CBCT to confirm the diagnosis and to be used as a standardized follow up record Patients were equally randomized between study groups (Propolis), (Nano-propolis) and comparator group (saline) as final irrigants as follows:
group I (comparator) comprise 28 patients in which single visit regeneration procedures was performed using 17%EDTA and saline was used as final irrigation material.
group II (Intervention 1 )comprise 28 patients in which single visit regeneration procedures was performed and propolis was used as final irrigation material.
group III (Intervention 2) comprise 28 patients in which single visit regeneration procedures was performed using Nano-propolis was used as final irrigation material.
PRF was prepared by drawing blood into a 10 m ltest tube and centrifuged immediately using a table top centrifuge at 3000 rpm for 10 minutes. The freshly prepared PRF membrane was fragmented, fragments were placed incrementally in the canal using a hand plugger size 40 and up to the level of the CEJ. Collacote was then placed over the blood clot, followed by a 3mm thick layer of Biodentine Teeth were immediately restored with resin modified glass ionomer cement and the final filling will be accomplished with resin with adhesive for permanent restoration.
Variables was measured at baseline and at 1, 3, 6, and 12months after the treatment. At each appointment, a clinical examination, a periapical radiograph, and pulp tests (thermal and electric) was performed. CBCT images was obtained at baseline and at 6 and 12 months after the treatment to evaluate the periapical bone healing.
Results: The periapical healing at 12 months follow up showed total healing of periapical lesions in 57.1% (48 patients) in all groups. 14.3% (12 patients) showed moderate healing with more than 50% decrease in size of periapical lesions. Mild healing has been reported in 19% (16 patients) only of treated cases with decrease in size of periapical lesion less than 20% .Periapical healing was not reported in 8 patients of treated cases. The control group showed the highest percentage of cases with mild and no periapical healing with reported 12 cases. Nano-propolis group showed the most favorable overall outcomes with almost 85.7 % of cases showed a degree of total and moderate healing at 12 months follow up with no failed cases. All teeth included in our study showed 100% survival rate, however ,none of them responded positively to electric or thermal pulp tests.