الفهرس | Only 14 pages are availabe for public view |
Abstract Trigeminal neuralgia (TGN) is the most common neuralgia, with an annual incidence of 5/100000. The International Association for the Study of Pain (IASP) defines TGN as sudden, usually unilateral, severe, brief, stabbing, and recurrent episodes of pain in the distribution of one or more branches of the trigeminal nerve. Paroxysmal attacks are frequently triggered by chewing, brushing teeth, laughing, talking, and even smiling.The pathophysiology of TGN remains unclear. According to the ignition theory,” TGN is the result of abnormalities in the afferent neurons of the trigeminal root or ganglion. Any injury to the axons can make them hyperexcitable, leading to this painful neuropathic condition. Some of the risk factors in developing TGN are multiple sclerosis (MS), increased age, stroke,hypertension, and tumors in the region of the trigeminal nerve root.In Idiopathic Trigeminal Neuralgia (ITGN), vascular compression of the nervr is the usual etiology, while secondary TGN is related to the compression by tumor or MS |