الفهرس 
Effect of magnesium sulphate added to mepivacaine hydrochloride on inferior alveolar nerve block success in patients with symptomatic irreversible pulpitis in mandibular molars: A Randomized clinical trial
ABSTRACTOnly 14 pages are availabe for public view
 |  | from | 130 |  |  |
| | | from | 130 | | |
Abstract
Aim: The aim of the present study was to assess the success of inferior alveolar nerve block
(IANB) when adding magnesium sulphate (MgSO4) to mepivacaine HCl in comparison to
mepivacaine HCl alone in patients with symptomatic irreversible pulpitis in mandibular molars.
Methodology: Forty-eight patients diagnosed with symptomatic irreversible pulpitis (SIP) were
assigned randomly into 2 groups (n=24). Initial pain data were diagnosed with cold spray and
collected on a numerical rating scale (NRS) chart. Both groups received 1.8 ml of local anesthetic
solution as a standard IANB. In the control group, the local anesthetic solution contained 1.8%
mepivacaine HCl while in the experimental group contained 1% MgSO4 and 1.8% mepivacaine HCl.
Pain was assessed 15 minutes after injection using cold spray, during access and canal negotiation on
a NRS chart. Success of local anesthesia was defined as recording no (NRS =0) or mild pain (NRS
ranges from 1-3). If the patient reported moderate or severe pain, the anesthetic blockade was
categorized as a failure and a supplemental anesthesia was given.
Results: The success of pulpal anesthesia with IANB was 70.8% for the MgSO4 group and 50%
for the control group. There was no significant difference in the effectiveness of the IANB between
the 2 groups (P > 0.05).
Conclusion: The combination of mepivacaine–MgSO4 achieved a higher success rate for IANB
than that of mepivacaine alone, but there was no significant difference in the anesthetic efficacy
between the control and experimental solutions, and neither of the tested solutions was able to achieve
100 % anesthetic success in patients with SIP in mandibular molars.