الفهرس | Only 14 pages are availabe for public view |
Abstract S UMMARY ommon variable immune deficiency (CVID) is a primary immunodeficiency disorder characterized by recurrent infections, low levels of immunoglobulins, and poor antibody response to vaccination. Immune thrombocytopenic purpura (ITP) is an autoimmune disorder characterized by low platelet counts, leading to spontaneous bleeding or easy bruising. ITP can occur in patients with CVID and presents unique challenges in diagnosis and management. This study aimed to investigate the prevalence of CVID among patients with ITP and identify potential risk factors or clinical associations. The study included 90 adult patients with ITP and found that CVID was prevalent in this population. This research is significant as it may improve the understanding of the underlying mechanisms of ITP and CVID, as well as guide clinical management and treatment decisions for patients with these conditions. Close monitoring of platelet counts and bleeding symptoms is necessary in patients with suspected ITP and CVID. The most common medications prescribed for patients with ITP in this study were also identified. C Summary 105 In conclusion, the results revealed that a small proportion of ITP patients may have underlying immunodeficiency disorders, such as selective Ig deficiency or CVID, with 10% showing below-normal levels of IgG, 11.1% showing below-normal levels of IgM, and 3.3% showing below-normal levels of IgA. In conclusion, these findings highlight the importance of considering immunodeficiency disorders in patients with ITP and the need for further investigation and management in such cases |